Yu‐Chuan Chang

PGSbuilder provides a web platform for GWAS and PRS analysis, enabling medical professionals to assess genetic risk using variant annotations and multiple PRS methods.

This paper introduces MHCfovea, a deep learning framework that connects HLA alleles with binding motifs, revealing critical polymorphic residues for antigen discovery and vaccine design.

This study develops a deep learning model to predict enhancer activity in new cell types by integrating DNase data across multiple cell types.

GenEpi detects gene-based epistasis using machine learning, outperforming existing methods on simulated data and identifying disease-related variants in Alzheimer's disease.