Soraya Seedat

The paper examines how childhood maltreatment affects brain structure in 3,711 individuals with MDD and PTSD, finding age- and sex-specific brain morphometric differences.

This study conducts an epigenome-wide association study of PTSD in a South African population, identifying epigenetic changes and accelerated DNA methylation age associated with PTSD severity and comorbid metabolic syndrome.

This study finds smaller total and subregional cerebellar volumes in PTSD compared to controls using a large dataset and advanced parcellation methods.

This paper compares four methods for harmonizing cortical thickness data across multiple sites and finds that ComBat-GAM is most effective in detecting case-control differences and age-related cortical thinning.

The paper identifies lincRNAs and their mRNA targets involved in fear extinction induced by D-cycloserine and links them to neurological and psychiatric traits.

This study identifies hippocampal subfield volume differences in PTSD and depression across 31 cohorts, finding depression has a stronger effect than PTSD, especially in CA1, with comorbid cases showing more pronounced changes.

This study identifies reduced fractional anisotropy in the tapetum region of the corpus callosum in PTSD patients using a large multi-cohort analysis of diffusion MRI data.