Author

Naftali Stern

Tel Aviv UniversityORCID 0000-0002-5123-3176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:deconvolution· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Organism:multiple species· 1

Frequent Co-Authors

Gabi SheferiD· 3 shared Elad SegeviD· 2 shared Metsada Pasmanik‐ChoriD· 2 shared Tamar ShahaliD· 2 shared Thomas KonstantinovskyiD· 2 shared Yonit MarcusiD· 2 shared Yuval EbensteiniD· 2 shared Assaf BuchiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersPhysiology

Gabi SheferORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintJun 23, 2026

The Metabolic Scope Theory of Aging: Rising Mitochondrial Impedance Compresses Metabolic Reserve to Constrain Lifespan

Gilad Lehmann, Yona Greenman, Izhar Shtrom…·Gabi Shefer

This paper proposes the Metabolic Scope Theory of Aging (MSTA) to explain lifespan variation by linking mitochondrial bioenergetic reserve, stability, and pace across species.

DOI 10.64898/2026.06.18.730063

multiple speciesstatistical model

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GenomicsbioRxivPreprintOct 2, 2022

Epigenetic aging waves:Artificial intelligence detects clustering of switch points in DNA methylation rate in defined sex-dependent age periods

Elad Segev, Tamar Shahal, Thomas Konstantinovsky…·Naftali Stern

The paper uses machine learning to identify age-related switch points in DNA methylation trends, revealing three sex-dependent waves of epigenetic aging.

1 citation

humanDNA methylation

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Developmental BiologyEpigenetics & ChromatinPeer-reviewedMar 7, 2022

Deconvolution of the epigenetic age discloses distinct inter-personal variability in epigenetic aging patterns

Tamar Shahal, Elad Segev, Thomas Konstantinovsky…·Naftali Stern

The paper deconvolves epigenetic age to identify CpG sites responsible for accelerated and decelerated aging, revealing inter-personal variability in aging patterns.

13 citations

humanDNA methylation

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