Author

Wendao Liu

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-5124-9338Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Zhongming ZhaoiD· 4 shared AR WalleriD· 1 shared Baylee J. O’BrieniD· 1 shared Casey Van KirkiD· 1 shared Chia-Hao TungiD· 1 shared Curtis Jackson WrayiD· 1 shared Eva Marie Sevick-MuracaiD· 1 shared Fabian Joachim TheisiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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4 shared papersBioinformatics

Zhongming ZhaoORCID

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4 papers

Recent·Most cited

Combination Immunotherapy Enhances Serial Radiofrequency Ablation Induced Systemic Antitumor Immunity in Pancreatic Cancer

Lincoln N. Strickland, MacKenzie V. Demmel, Wendao Liu, AR Waller, Shwetapadma Dash, Khadija Shahab Turabi, Urvinder Kaur Sardarni, Nicolette R. Mardik, Casey Van Kirk, Baylee J. O’Brien, Julie Rowe, Putao Cen, Kelsey A. Klute, Jesse L. Cox, Zhongming Zhao, , Jennifer M. Bailey

This study shows combination immunotherapy enhances systemic antitumor immunity induced by serial radiofrequency ablation in pancreatic cancer by targeting CD73, PD-L1, and CSF1R.

bioRxiv · Jul 1, 2026 · PreprintCancer Biology

Turep: Detecting cross-cancer tumor-reactive T cells in single-cell and spatial transcriptomics data

Wendao Liu, Chia-Hao Tung, Eva Marie Sevick-Muraca, Zhongming Zhao

Turep identifies tumor-reactive T cells in single-cell and spatial transcriptomics data across cancers, showing improved prediction of immunotherapy response.

bioRxiv · Apr 24, 2026 · PreprintBioinformatics

FADVI: disentangled representation learning for robust integration of single-cell and spatial omics data

Wendao Liu, Gang Qu, Lukas Mikolaj Simon, Fabian Joachim Theis, Zhongming Zhao

FADVI integrates single-cell and spatial omics data by disentangling batch effects from biological signals, outperforming existing methods across multiple datasets.

bioRxiv · Nov 3, 2025 · PreprintBioinformatics

Scupa: Single-cell unified polarization assessment of immune cells using the single-cell foundation model

Wendao Liu, Zhongming Zhao

Scupa assesses immune cell polarization using a foundation model, identifying cytokine-driven states across species and conditions.

Bioinformatics · Feb 25, 2025Peer-reviewedBioinformatics