Urvinder Kaur Sardarni

This study shows that combining CD73 and RAS(ON) inhibition reduces tumor growth and immune suppression in pancreatic cancer by targeting KRAS-MAPK driven CD73 signaling.

This study shows pulsed field ablation (PFA) reduces tumor growth in a mouse model of pancreatic ductal adenocarcinoma by altering the tumor microenvironment and stromal cells.

This study shows combination immunotherapy enhances systemic antitumor immunity induced by serial radiofrequency ablation in pancreatic cancer by targeting CD73, PD-L1, and CSF1R.

This study shows that ketogenic and high-fat diets accelerate pancreatic cancer progression in mice, leading to more aggressive tumors and a pro-inflammatory microenvironment.

The paper investigates tissue-specific metabolic reprogramming and gut dysbiosis in hamsters infected with SARS-CoV-2 variants, revealing differences in viremia, metabolic responses, and microbiota composition between delta and omicron variants.