Jennifer M. Bailey

This study shows that combining CD73 and RAS(ON) inhibition reduces tumor growth and immune suppression in pancreatic cancer by targeting KRAS-MAPK driven CD73 signaling.

This study shows pulsed field ablation (PFA) reduces tumor growth in a mouse model of pancreatic ductal adenocarcinoma by altering the tumor microenvironment and stromal cells.

This study shows combination immunotherapy enhances systemic antitumor immunity induced by serial radiofrequency ablation in pancreatic cancer by targeting CD73, PD-L1, and CSF1R.

This study shows that ketogenic and high-fat diets accelerate pancreatic cancer progression in mice, leading to more aggressive tumors and a pro-inflammatory microenvironment.

This study identifies 15 novel ductal cell populations in the mouse pancreas using scRNA-seq and investigates their roles in regeneration and exocrine pathogenesis.

This study shows that Adar1 deletion in mice causes exocrine pancreas degeneration through Mavs-dependent interferon signaling, which is rescued by concurrent Mavs deletion.