ImmunologybioRxivPreprint
C3a receptor signalling in ObRb-expressing neurons promotes leptin resistance and obesity-associated cardiac remodelling
Elias Rawish, Carolin Gragoll, Michael Schneider…·Ingo Eitel
This study identifies C3aR signaling in ObRb-expressing neurons as a pathway contributing to leptin resistance and obesity-related cardiac remodeling, with potential therapeutic implications.