Author

Ana J. García‐Sáez

University of CologneORCID 0000-0002-3894-5945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Andreas JenneriD· 1 shared Anja Ciprinidis· 1 shared Anna Schaedler· 1 shared Aslihan Ugun‐KlusekiD· 1 shared Astrid C SchaussiD· 1 shared Benjamin Schmidt· 1 shared Betül Uysal· 1 shared Boris MačekiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

Andreas JennerORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 12, 2025

Mechanical forces drive mitochondrial matrix extrusion and apoptotic pore growth

Andreas Jenner, Timo Dellmann, Hyuntae Kim…·Ana J. García‐Sáez

The paper investigates the role of mechanical forces in mitochondrial inner membrane extrusion and apoptotic pore growth using CLOSE microscopy.

1 citation

imagingmicroscopy & imaging analysis

𝕏 PostBluesky

Cell BiologyThe EMBO JournalPeer-reviewedFeb 21, 2025

Spatio-temporal analysis of the innate immune response to cytoplasmic dsDNA using a novel cGAMP biosensor

Steve Smarduch, Sergio David Moreno-Velásquez, Doroteja Ilic…·Sergio P. Acebrón

The paper develops a fluorescent cGAMP biosensor to monitor cGAS-STING signaling dynamics in real-time and across different cellular contexts.

18 citationstop 3%

humanfluorescence / live-cell microscopy

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BiophysicsLangmuirPeer-reviewedNov 12, 2024

Lipid oxidation alters membrane mechanics favoring permeabilization

Sara Lotfipour Nasudivar, Lohans Pedrera, Ana J. García‐Sáez

This study investigates how lipid oxidation affects membrane mechanics and pore formation by analyzing model membrane systems.

27 citations

experimental assaycell signaling & trafficking

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NeurosciencebioRxivPreprintOct 22, 2019

PINK1 Regulates Dopamine and Lipids at Mitochondria to Maintain Synapses and Neuronal Function

Christine Bus, Sven Geisler, Marita Pauline Feldkaemper…·Julia Catherine Fitzgerald

This study identifies PINK1's role in regulating mitochondrial function, lipid metabolism, and dopamine homeostasis in dopaminergic neurons, showing that cholesterol depletion can reverse PINK1-related phenotypes.

3 citations

humanexperimental assay

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