Britta Brügger

This study shows that the N-terminus of Wnt proteins determines their secretion and signaling properties, with Wnt11's N-terminus enabling Evi/Wls-independent secretion and Frizzled 6 activation.

This study identifies DHHC20 interaction partners in T cells, showing it interacts with Gsβ1γ2 and suggests a model for its role in palmitoylation.

The paper identifies 218 C16:0-acylated and 308 C18-lipid-acylated proteins, showing widespread competition for acylation across the proteome.

This study identifies how IFITM3 inhibits influenza virus entry by stabilizing hemifusion through lipid sorting in endosomal membranes.

This study identifies PINK1's role in regulating mitochondrial function, lipid metabolism, and dopamine homeostasis in dopaminergic neurons, showing that cholesterol depletion can reverse PINK1-related phenotypes.