Cancer BiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewed
Genetically induced mouse model for colon-specific epithelial cell tumorigenesis driven by loss of K8 and Apc
Mina Tayyab, Mira M. E. Minkkinen, Carl-Gustaf A. Stenvall…·Diana M. Toivola
This study develops a genetic, colon-specific mouse model of colorectal cancer driven by K8 and Apc loss, showing increased tumorigenesis and reduced K8 expression in human patients.
DOI 10.1016/j.jcmgh.2025.101716