Adult mice with neonatal-like T cell subsets exhibit increased susceptibility to Bordetella pertussis and influenza infection
Matthew R. Hansen, Colleen J. Sedney, Shiyun Xiao, Disha BR Prasad, Wen Zhang, Kalyan Kumar Dewan, Jillian Masters, Maiya Callender, Eric T. Harvill, Kimberly D. Klonowski, Nancy Ruth Manley
This study shows that adult mice with neonatal-like T cell subsets are more susceptible to Bordetella pertussis but not influenza, highlighting the role of thymic development in immune responses.
The Journal of Immunology · Mar 1, 2026Peer-reviewedImmunology