Nancy Ruth Manley

This study shows that adult mice with neonatal-like T cell subsets are more susceptible to Bordetella pertussis but not influenza, highlighting the role of thymic development in immune responses.

The paper examines molecular and cellular changes in thymic stromal and hematopoietic cells during the perinatal to juvenile transition in mice and humans, identifying key pathways and signaling changes.

This study investigates the role of Dicer-mediated mTORC1 signaling in parathyroid function using genetic mouse models and clinical data, showing its critical role in maintaining gland integrity and response to CKD.

This study shows Foxn1 overexpression in TECs promotes proliferation and differentiation but does not prevent aging-related thymic involution.

This study characterizes the reprogramming of mouse fibroblasts into thymic epithelial cells (TECs) by analyzing gene expression changes and identifying factors that enhance the process.

This study shows Notch1 signaling is essential for specifying and expanding the medullary thymic epithelial cell (mTEC) progenitor pool during mouse fetal development.