Impact of HIV-1 infection on the microglia transcriptome: induction of microRNA-23b leads to G3BP2-mediated stress granules assembly disruption
Robert Lodge, William G. Branton, Frank Kirchhoff…·Éric A. Cohen
This study shows HIV-1 infection alters microglia transcriptome by upregulating microRNA-23b, which disrupts G3BP2 and stress granule assembly, promoting HIV-1 replication.