Author

Noam Steinberg

University of AlbertaORCID 0000-0002-6901-7316Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Danny GalleguillosiD· 2 shared Simonetta SipioneiD· 2 shared Asifa K. ZaidiiD· 1 shared Christopher PoweriD· 1 shared Fabrizio GiulianiiD· 1 shared Gaurav ShrivastavaiD· 1 shared Kamaldeep DhamiiD· 1 shared Karin Rubinstein· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Danny GalleguillosORCID

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2 papers

Recent·Most cited

Naive Huntington's disease microglia mount a normal response to inflammatory stimuli but display impaired development of innate immune tolerance that can be counteracted by ganglioside GM1

Noam Steinberg, Danny Galleguillos, Asifa K. Zaidi, Simonetta Sipione

This study shows that naive HD microglia respond normally to inflammation but have impaired tolerance development, which can be reversed by GM1.

bioRxiv · Apr 5, 2023 · PreprintNeuroscience

Anti-inflammatory role of GM1 and modulatory effects of gangliosides on microglia functions

Danny Galleguillos, Qian Wang, Noam Steinberg, Gaurav Shrivastava, Kamaldeep Dhami, Karin Rubinstein, Fabrizio Giuliani, Matthew A. Churchward, Christopher Power, Kathryn G. Todd, Simonetta Sipione

This study shows that GM1 ganglioside administration reduces microglial inflammation and modulates microglial functions, suggesting therapeutic potential for neurodegenerative diseases.

bioRxiv · Mar 4, 2020 · PreprintNeuroscience