Natacha S. Ogando

Bovine H5N1 influenza viruses have adapted to more efficiently use receptors abundant in cattle

This study shows bovine H5N1 influenza viruses have adapted to efficiently use NeuGc receptors in cattle, enhancing replication without significantly altering zoonotic risk.

Progressive Post-Acute Gut Microbiome Disruption Following SARS-CoV-2 Infection in Mice

This study tracks gut microbiome changes in mice after SARS-CoV-2 infection, showing progressive dysbiosis and functional shifts over time.

Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication

This study identifies critical residues in the nsp14 N7-MTase domain essential for betacoronavirus replication and suggests potential drug targets.

Genome-wide mapping of therapeutically-relevant SARS-CoV-2 RNA structures

This study maps SARS-CoV-2 RNA structures at single-base resolution using SHAPE-MaP, identifies druggable pockets and conserved elements, and highlights targets for antisense therapeutics.