Molecular BiologyNucleic Acids ResearchPeer-reviewed
Retroviral adapters hijack the RNA helicase UPF1 in a CRM1/XPO1 dependent manner and reveal proviral roles of UPF1.
Léa Prochasson, Makram Mghezzi-Habellah, Armelle Roisin…·Vincent Mocquet
This paper shows that HTLV-1 Rex hijacks CRM1 to retain UPF1 in the nucleus, inhibiting NMD and enabling UPF1 to support viral replication.
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