Chronic morphine induces adaptations in opioid receptor signaling in a thalamo-cortico-striatal circuit that are projection-dependent, sex-specific and regulated by mu opioid receptor phosphorylation
Elizabeth R. Jaeckel, Erwin R. Arias‐Hervert, Alberto L. Perez-Medina…·William T. Birdsong
This study shows chronic morphine induces sex-specific, projection-dependent adaptations in MOR signaling in thalamo-cortico-striatal circuits, mediated by MOR phosphorylation.