William T. Birdsong

This study investigates the effects of the ANK3 p.W1989R variant in human and mouse models, showing altered somatostatin interneuron connectivity and function linked to bipolar disorder.

This study shows that DOR on PV interneurons are necessary for the convulsant and anxiolytic effects of SNC80, but not for locomotor or respiratory responses.

This study examines how opioid receptors modulate excitatory synaptic transmission in the claustro-cingulate pathway using spatial transcriptomics and electrophysiology in mice, revealing receptor-specific effects.

This study shows chronic morphine induces sex-specific, projection-dependent adaptations in MOR signaling in thalamo-cortico-striatal circuits, mediated by MOR phosphorylation.

This study shows that endogenous opioid Met-Enkephalin modulates thalamo-cortical excitation-inhibition balance by preferentially inhibiting GABAergic transmission in the ACC.

This study shows that opioid receptors inhibit adenosine signaling in the striatum by reducing cAMP, specifically affecting D1R-positive medium spiny neurons.

This study investigates how opioids modulate glutamate transmission in thalamo-cortico-striatal circuits in mice, revealing distinct effects of mu- and delta-opioid receptors on neural activity.