Caitlin A. Murphy

Enhanced food motivation in obese mice is controlled by D1R expressing spiny projection neurons in the nucleus accumbens.

This study shows that obese mice exhibit increased activity in D1R-expressing spiny projection neurons in the nucleus accumbens during food seeking, which enhances food motivation and contributes to diet-induced obesity.

Corticothalamic gating of population auditory thalamocortical transmission in mouse

The paper investigates corticothalamic gating of auditory thalamocortical transmission in mice, finding that corticothalamic feedback inhibition controls population responses to sensory stimuli.

Electrophysiological signatures of acute systemic lipopolysaccharide: potential implications for delirium science

This study examines how lipopolysaccharide (LPS) affects electrophysiological activity in mice, linking inflammation to changes in slow wave activity and potential delirium mechanisms.

Modeling features of addiction with an oral oxycodone self-administration paradigm

This paper introduces an oral oxycodone self-administration paradigm in mice to model prescription opioid use and its transition to abuse.

Optogenetic activation of afferent pathways in brain slices and modulation of responses by volatile anesthetics

This paper describes a protocol to study how volatile anesthetics affect evoked responses in brain slices using optogenetic activation of afferent pathways.

Cell type-specific effects of isoflurane on two distinct afferent inputs to cortical layer 1.

This study examines how isoflurane affects synaptic responses in different cell types and cortical layers in mouse neocortex.

Evidence that PV+ cells enhance temporal population codes but not stimulus-related timing in auditory cortex

The paper shows PV+ interneurons enhance spatio-temporal spike patterns in pyramidal cells during network bursts but do not improve stimulus-related timing.