Michel Baudry

Calpain-2 inhibition or deletion enhances levels of the transcription Factor, MEIS2, and stimulates neurogenesis

This study shows that inhibiting or deleting calpain-2 increases MEIS2 levels and promotes neurogenesis in adult mice by enhancing dendritic spine maturation.

Identification and neuroprotective properties of NA-184, a selective calpain-2 inhibitor

The paper identifies NA-184, a selective calpain-2 inhibitor, and shows its neuroprotective effects in traumatic brain injury models.

UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity

This study shows that UBE3A regulates mTORC1 activity and synaptic plasticity by ubiquitinating and degrading p18, a Ragulator subunit, in Angelman syndrome mice.