Systems BiologybioRxivPreprint
Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele.
Anand Chellappan Reghuvaran, Ashwani Kumar, Qisheng Lin…·Madhav C. Menon
This study identifies the Shroom3 ASD2-domain as critical for profibrotic function in CKD through ROCK activation, showing motif-specific roles in renal fibrosis and albuminuria.
2 citations