Author

Anand Chellappan Reghuvaran

Yale UniversityORCID 0000-0002-5656-0205Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Cijiang HeiD· 3 shared Hongmei ShiiD· 3 shared Madhav C. MenoniD· 3 shared Chengguo WeiiD· 2 shared E. M. TanviriD· 2 shared Gabriel BarsottiiD· 2 shared John F. PelliD· 2 shared Lloyd G. CantleyiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersSystems Biology

Cijiang HeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A T-cell Intrinsic Role for APOL1 Risk Alleles in Allograft Rejection

John F. Pell, E. M. Tanvir, Zhengliang Sun, Irene Chernova, Anand Chellappan Reghuvaran, Soichiro Nagata, Mateus Guerra, John Choi, Soltan Al Chaar, Hiroki Mizuno, Ke Dong, Xin Tian, Reika Ishibe, Barbara Franchin, Paolo Cravedi, , Madhav C. Menon

This study identifies a T-cell intrinsic mechanism by which APOL1 risk alleles contribute to kidney rejection through altered calcium signaling and T-cell activation.

American Journal of Transplantation · Aug 1, 2025Peer-reviewedImmunology

Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele.

Anand Chellappan Reghuvaran, Ashwani Kumar, Qisheng Lin, Nallakandi Rajeevan, Zeguo Sun, Hongmei Shi, Gabriel Barsotti, E. M. Tanvir, John F. Pell, Sudhir Perincheri, Chengguo Wei, Marina Planoutene, Anne Eichmann, Valeria R. Mas, Weijia Zhang, , Madhav C. Menon

This study identifies the Shroom3 ASD2-domain as critical for profibrotic function in CKD through ROCK activation, showing motif-specific roles in renal fibrosis and albuminuria.

bioRxiv · Nov 22, 2024 · PreprintSystems Biology

AMP-Kinase mediates regulation of glomerular volume and podocyte survival

Khadija Banu, Qisheng Lin, John M. Basgen, Marina Planoutene, Chengguo Wei, Anand Chellappan Reghuvaran, Felipe Garzon, Aitor Garcia, Nicholas H. Chun, Arun Čumpelik, Hongmei Shi, Andrew Santaneusio, Weijia Zhang, Bhaskar C. Das, Fadi E. Salem, , Madhav C. Menon

The paper investigates the role of AMP-Kinase in regulating glomerular volume and podocyte survival through experimental models and biochemical analysis.

bioRxiv · May 21, 2021 · PreprintSystems Biology