Author

Katarina Lamb

Autolus (United Kingdom)ORCID 0000-0002-5155-069XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Christopher G. AlleniD· 2 shared Farhaan ParekhiD· 2 shared James SillibourneiD· 2 shared Martin A. PulèiD· 2 shared Shaun P CordobaiD· 2 shared Simon ThomasiD· 2 shared Abigail Dolor· 1 shared Alastair HotblackiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Christopher G. AllenORCID

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2 papers

Recent·Most cited

Molecular BiologyACS Chemical BiologyPeer-reviewedJan 20, 2024

Designer small molecule control system based on Minocycline induced disruption of protein-protein interaction.

Ram Jha, Alexander Kinna, Alastair Hotblack…·Martin A. Pulè

The paper develops a small-molecule control system using minocycline to disrupt protein-protein interactions for reversible and dose-dependent control of therapeutic applications.

8 citations

protein structureexperimental assay

𝕏 PostBluesky

Synthetic BiologyMolecular Therapy — Nucleic AcidsPeer-reviewedApr 25, 2023

Novel Fas-TNFR chimeras that prevents Fas ligand-mediated kill and signals synergistically to enhance CAR T-cell efficacy

Callum McKenzie, Mohamed El-Kholy, Farhaan Parekh…·Martin A. Pulè

This study identifies Fas-CD40 as a chimeric Fas-TNFR that prevents Fas ligand-mediated kill and enhances CAR T-cell efficacy through synergistic signaling.

15 citations

humanexperimental assay

𝕏 PostBluesky