Author

Hugh Cottingham

Monash UniversityORCID 0000-0002-5156-1970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Research Focus:clustering· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Kathryn E. HoltiD· 2 shared Louise M. JuddiD· 2 shared Ryan R. WickiD· 2 shared Thomas D. StantoniD· 2 shared Anton Yariv PelegiD· 1 shared Ben VezinaiD· 1 shared David M. AanenseniD· 1 shared Ebenezer Foster-NyarkoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Kathryn E. HoltORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologymSystemsPeer-reviewedJan 8, 2025

Targeted sequencing of Enterobacterales bacteria using CRISPR-Cas9 enrichment and Oxford Nanopore Technologies

Hugh Cottingham, Louise M. Judd, Jessica A. Wisniewski…·Jane Hawkey

This paper demonstrates that CRISPR-Cas9 enrichment combined with Oxford Nanopore sequencing improves detection of AMR genes and MLST in patient samples compared to unenriched sequencing.

17 citationstop 2%

humanlong-read sequencing

𝕏 PostBluesky

GenomicsMicrobial GenomicsPeer-reviewedFeb 8, 2023

Nanopore-only assemblies for genomic surveillance of the global priority drug-resistant pathogen, Klebsiella pneumoniae

Ebenezer Foster-Nyarko, Hugh Cottingham, Ryan R. Wick…·Kathryn E. Holt

This study evaluates ONT-only assemblies for genomic surveillance of Klebsiella pneumoniae, showing reliable MLST, K type, and AMR detection but challenges in cluster detection.

54 citationstop 3%

bacteria (other)whole-genome sequencing

𝕏 PostBluesky