Thomas D. Stanton

A curated Kaptive-compatible database of 88 capsule (K) loci types 97.6% of dereplicated Klebsiella oxytoca species complex genomes, versus 50.3% typed with the existing K. pneumoniae database.

Kaptive v3 improves antigen typing accuracy and speed for KpSC genomes by addressing assembly fragmentation issues, enabling efficient in silico serotyping.

This paper demonstrates that CRISPR-Cas9 enrichment combined with Oxford Nanopore sequencing improves detection of AMR genes and MLST in patient samples compared to unenriched sequencing.

This study evaluates ONT-only assemblies for genomic surveillance of Klebsiella pneumoniae, showing reliable MLST, K type, and AMR detection but challenges in cluster detection.