Author

Jessica A. Wisniewski

Monash UniversityORCID 0000-0002-9923-6579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Approach:graph neural network· 1 Organism:human· 1

Frequent Co-Authors

Anton Yariv PelegiD· 2 shared Ben VezinaiD· 2 shared Kathryn E. HoltiD· 2 shared Matthew H. ParkeriD· 2 shared Nenad MaćešićiD· 2 shared Adam W. J. JenneyiD· 1 shared Anna G. GreeniD· 1 shared David L. DoweiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Anton Yariv PelegORCID

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Author profile →

3 papers

Recent·Most cited

AMR-GNN: A multi-representation graph neural network framework to enable genomic antimicrobial resistance prediction

Hoai-An Nguyen, Anton Y. Peleg, Jessica A. Wisniewski, Xiaoyu Wang, Zhikang Wang, Luke V. Blakeway, Gnei Z. Badoordeen, Ravali Theegala, Nhu Quynh Doan, Matthew H. Parker, Anna G. Green, Jiangning Song, David L. Dowe, Nenad Maćešić

AMR-GNN predicts antimicrobial resistance using a graph neural network framework that integrates multiple genomic representations from whole-genome sequencing data.

Nature Communications · Mar 6, 2026Peer-reviewedGenomics

Targeted sequencing of Enterobacterales bacteria using CRISPR-Cas9 enrichment and Oxford Nanopore Technologies

Hugh Cottingham, Louise M. Judd, Jessica A. Wisniewski, Ryan R. Wick, Thomas D. Stanton, Ben Vezina, Nenad Maćešić, Anton Yariv Peleg, Iruka N. Okeke, Kathryn E. Holt, Jane Hawkey

This paper demonstrates that CRISPR-Cas9 enrichment combined with Oxford Nanopore sequencing improves detection of AMR genes and MLST in patient samples compared to unenriched sequencing.

mSystems · Jan 8, 2025Peer-reviewedMicrobiology

Wild type domestication: loss of intrinsic metabolic traits concealed by culture in rich media

Ben Vezina, Helena B. Cooper, Jessica A. Wisniewski, Matthew H. Parker, Adam W. J. Jenney, Kathryn E. Holt, Kelly L. Wyres

The paper identifies hidden metabolic mutations in Klebsiella pneumoniae cultures grown in rich media, showing how these mutations can persist undetected and affect auxotrophy.

Microbial Ecology · Nov 20, 2024Peer-reviewedMicrobiology