Vibha N. Lama

CytoSignal detects and quantifies ligand-receptor signaling interactions at cellular resolution from spatial transcriptomic data, enabling spatial gradient analysis and temporal dynamics prediction.

The paper characterizes CXCL12-expressing mesenchymal stromal cells and their role in supporting antibody-secreting cell niches in rejecting lung allografts.

This study induces and engrafts human pluripotent stem cell-derived lung bud tip progenitor-like cells in vitro and in vivo, showing their similarity to native lung tissue and multi-lineage potential.