Jifu Duan

This study identifies a histidine-mediated pendulum mechanism in [FeFe]-hydrogenases that enhances catalytic activity by facilitating proton transfer.

The paper presents a high-resolution crystal structure of CbA5H in the O2-stable Hinact state, showing direct thiol binding to the active site iron, supported by DFT calculations.

This study identifies ToHydA, an O2-stable [FeFe]-hydrogenase from Thermosediminibacter oceani, and reveals structural features that protect the H-cluster from O2-induced degradation.