Author

Lucas Di Meglio

InsermORCID 0000-0002-5158-8612Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Astride Perrot· 1 shared Benoît Ho‐Tin‐NoéiD· 1 shared Dorothée FailleiD· 1 shared Fatima Zemali· 1 shared François DelvoyeiD· 1 shared Jasmina Rogozarski· 1 shared Jean‐Philippe DésillesiD· 1 shared Julien LabreucheiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

Astride Perrot

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1 paper

Recent·Most cited

PathologybioRxivPreprintMar 28, 2025

Neutrophil extracellular traps block endogenous and intravenous thrombolysis-induced fibrinolysis in large vessel occlusion acute ischemic stroke

Jean‐Philippe Désilles, Mialitiana Solo Nomenjanahary, Astride Perrot…·Benoît Ho‐Tin‐Noé

This study shows that neutrophil extracellular traps (NETs) inhibit fibrinolysis during intravenous thrombolysis in acute ischemic stroke by sequestering tPA and plasminogen, and that DNase 1 can enhance thrombolysis by removing NETs.

DOI 10.1101/2025.03.28.646062

humanproteomics

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