EBV reprograms autoreactive B cells as antigen presenting cells in multiple sclerosis
Shady Younis, Sajede Rasouli, Jacob W. Loeffler, Neda Sattarnezhad, Ya’el Courtney, Salvinaz Islam Moutusy, Shaghayegh Jahanbani, Mahesh Pandit, Anna J. Tomczak, Heidi Wong, Orr Sharpe, Paul J. Utz, Eric Meffre, Lucas B. Kipp, Jeffrey Dunn, , William H. Robinson
The paper shows EBV infects and reprograms autoreactive B cells into antigen-presenting cells in MS, driving pathogenic T cell responses.
bioRxiv · Feb 12, 2026 · PreprintImmunology