Author

Zhenquan Jia

University of North Carolina at GreensboroORCID 0000-0002-5187-1549Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ajmal KhaniD· 2 shared Kerui Wu· 2 shared Norman Chiu· 2 shared Warren S. VidariD· 2 shared Chunjiang Zhu· 1 shared Delicia Esther Cardenas Vasquez· 1 shared Frank Morales Shnaider· 1 shared Gordon Zheng· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersMolecular Biology

Ajmal KhanORCID

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Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 22, 2026

A Graph-based QSAR Modeling Pipeline for Predicting In vitro PubChem Assays and In vivo Human Hepatotoxicity: Mechanistic Analysis of Caspase-3/7 Activation

Yamini Chitikela, Chunjiang Zhu, Zhenquan Jia

This paper develops a graph-based QSAR pipeline to predict in vitro Caspase-3/7 activation and in vivo hepatotoxicity, showing improved performance over classical models.

DOI 10.64898/2026.06.10.731399

humangraph neural network

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Molecular BiologyEnvironmental PollutionPeer-reviewedSep 17, 2026

Polystyrene microplastic uptake drives Inflammatory, Epitranscriptomic, and Metabolic Reprogramming in Human Aortic Endothelial cells

Ajmal Khan, Grant Koher, Tariq Khan…·Zhenquan Jia

This study shows that polystyrene microplastics induce inflammatory, epitranscriptomic, and metabolic changes in human aortic endothelial cells, potentially contributing to cardiovascular disease.

DOI 10.1016/j.envpol.2026.129187

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJul 10, 2026

Chronic Polystyrene Nanoplastics Exposure Reprograms Gene Expression, Alternative Splicing, and Disrupts Host Microbiome Metabolic Networks to Promote Atherosclerosis in LDLr- Knockout Mice

Ajmal Khan, Delicia Esther Cardenas Vasquez, Yaru Si…·Zhenquan Jia

DOI 10.64898/2026.07.09.736446

mousebulk RNA-seq

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