Author

Eelco Christiaan Brand

Utrecht UniversityORCID 0000-0002-5195-0562Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bas OldenburgiD· 2 shared Femke van WijkiD· 2 shared Pieter MeysmaniD· 2 shared Romi VandoreniD· 2 shared Vincent M.L. Van DeureniD· 2 shared A Sophie Bakker· 1 shared Andrea E van der· 1 shared Anneke M P de Schryver· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Bas OldenburgORCID

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2 papers

Recent·Most cited

ImmunologyInflammatory Bowel DiseasesPeer-reviewedApr 14, 2026

Clonal overlap and convergent clustering of T-cell receptor signatures in Crohn's disease in monozygotic twins

Eelco Christiaan Brand, Romi Vandoren, Lisanne Lutter…·Marielle J L Romberg-Camps

This study analyzes T-cell receptor repertoires in monozygotic twins with and without Crohn's disease, finding increased TCR overlap in concordant pairs and identifying eight novel TCR clusters potentially linked to the disease.

2 citationstop 5%

humanCITE-seq

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BioinformaticsbioRxivPreprintSep 30, 2025

T cell-microbiome associations captured through T cell receptor convergence analysis

Romi Vandoren, My Kieu Ha, Vincent M.L. Van Deuren…·Pieter Meysman

The paper introduces AIRRWAS, a framework to identify T cell receptor convergence with bacterial genera, revealing reproducible associations across cohorts and functional T cell responses.

1 citation

humanbulk RNA-seq

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