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Longitudinal Profiling of CD4⁺ T Cell Responses Following de novo Yellow Fever Vaccination

This study tracks CD4+ T cell and IgG responses over time after yellow fever vaccination, showing peak activation at day 22 and long-term antibody persistence.

The T cell receptor repertoire captures healthy aging and CMV independently from epigenetic clocks

This study compares T cell receptor repertoire diversity and epigenetic clocks to assess healthy aging and CMV impact, finding higher TCR diversity in healthy elderly and CMV-related epigenetic aging.

T cell-microbiome associations captured through T cell receptor convergence analysis

The paper introduces AIRRWAS, a framework to identify T cell receptor convergence with bacterial genera, revealing reproducible associations across cohorts and functional T cell responses.

Generation of a T cell receptor, cytokine and cell repertoire synovial fluid atlas to define commonalities and dissimilarities between arthritic diseases through systems immunology approaches

The paper creates a synovial fluid TCR, cytokine, and cell repertoire atlas to compare disease mechanisms across arthritic conditions using systems immunology approaches.

Bridging immunotypes and enterotypes using a systems immunology approach

The paper links immunotypes and enterotypes through a systems immunology approach, showing they are orthogonal and connected via the blood transcriptome, with associations between specific bacteria and immune health.

T cell receptor-centric perspective to multimodal single-cell data analysis.

A TCR-first approach to single-cell data analysis improves identification of disease-specific TCR features and reveals previously unknown T-cell clusters and arrangements.

Linking myelin and Epstein-Barr virus specific immune responses in multiple sclerosis: insights from integrated public T cell receptor repertoires

This study analyzes T cell receptor repertoires in MS patients and controls to explore the relationship between EBV-specific and myelin-specific immune responses, finding distinct patterns associated with MS.