Lower pathogenicity but similar genital shedding of monkeypox virus clade Ib compared to clade Ia in a rodent model
Franziska Karola Kaiser, Shane Gallogly, Reshma Koolaparambil Mukesh…·Vincent Jacobus Munster
Author
National Institute of Allergy and Infectious DiseasesORCID 0000-0002-5195-5478Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Franziska Karola Kaiser, Shane Gallogly, Reshma Koolaparambil Mukesh…·Vincent Jacobus Munster
Franziska Karola Kaiser, Reshma Koolaparambil Mukesh, Shane Gallogly…·Vincent Jacobus Munster
This study investigates mpox virus transmission in prairie dogs, finding that anogenital mucosal routes lead to high shedding and efficient transmission.
Thomas Tipih, Vignesh Mariappan, Claude Kwe Yinda…·Kyle Rosenke
This study compares the virulence of recent bovine and non-bovine HPAI H5N1 isolates in mice, finding the bovine isolate causes severe respiratory and neurologic disease.
Reshma Koolaparambil Mukesh, Franziska Karola Kaiser, Jonathan E. Schulz…·Vincent Jacobus Munster
The study compares contact transmissibility of human, bovine, and mountain lion H5N1 isolates in Syrian hamsters, finding human isolate has higher contact transmissibility despite limited overall transmission.
Kerry Goldin, Sarah van Tol, Randall C. Johnson…·Neeltje van Doremalen
This study compares the tissue tropism of two HPAI H5N1 isolates in mice, finding that the bovine isolate replicates in the brain and causes more neurotropism and inflammation than the human isolate.
Arthur Wickenhagen, Meaghan Flagg, Julia Rebecca Port…·Vincent Jacobus Munster
This study evaluates the fitness and pathogenesis of Omicron variants in the upper and lower respiratory tracts, finding increased URT fitness with reduced lung pathology.