Peter Brown

This study investigates the aperiodic exponent of subthalamic field potentials in Parkinsonism across species, finding it reflects excitation/inhibition balance and could be a biomarker for adaptive deep brain stimulation.

This study investigates how subthalamic nucleus activity modulates action adaptation in Parkinson's patients during a force adaptation task, finding that reduced beta activity correlates with better adaptation.

This study shows that PPN LFP alpha and beta oscillations are rhythmically modulated by gait phase, with spatial specificity and increased modulation in regular stepping.

The paper shows increased theta/alpha synchrony in the habenula-prefrontal network during negative emotional stimulus processing in psychiatric patients.

This paper shows that average beta burst duration profiles reflect changes in the dynamics of beta oscillations between ON and OFF medication states in Parkinson's disease, linking them to motor impairment.

The paper investigates how implant location affects ECG contamination in neurostimulation systems, finding higher contamination in left-sided subclavicular implants compared to right-sided ones.

This study shows that neurofeedback training reduces STN beta bursts and improves movement speed in Parkinson's patients.

This study shows that alternating subthalamic nucleus deep brain stimulation can entrain stepping rhythms in Parkinson's patients, suggesting the STN's role in step timing control.

The paper investigates how Parkinson’s disease affects the sensitivity of subthalamic nucleus neurons to beta-frequency cortical input, showing increased phase-locking in PD patients and frequency-specific responses in rats.

The paper investigates how high-frequency activity in the basal ganglia co-varies with motor cortical beta oscillations during motor control and rest in Parkinson's patients.

This study compares acute effects of adaptive DBS (aDBS) with conventional DBS (cDBS) and no stimulation in Parkinson's disease patients, finding aDBS reduces motor symptoms more than cDBS and has fewer speech side effects.

The paper examines the structural and functional connectivity of the nucleus basalis of Meynert in Parkinson's disease dementia and Lewy body dementia using MEG and MRI tractography.

The paper identifies signatures of the hyperdirect pathway and its role in pathological network disruption in Parkinson's disease through multimodal analysis.

The paper uses a Wilson-Cowan model to analyze phase-dependent effects of deep brain stimulation in essential tremor patients, showing the model can predict tremor responses and fit patient data.

The paper examines cortico-basal-ganglia communication in Parkinson's patients, finding that gamma phase coupling between STN spikes and cortical activity precedes fast reaction times and is modulated by movement direction.

This paper predicts the effects of deep brain stimulation using a reduced coupled oscillator model and proposes a hybrid strategy for closed-loop DBS in essential tremor patients.

This study examines beta burst dynamics in the cortico-basal ganglia network of PD patients and rats, showing phase relationships and rhythmic activity patterns that correlate with motor impairment.

This paper decodes voluntary movements and postural tremor from thalamic LFPs to enable on-demand DBS for essential tremor without peripheral sensors.

This study investigates phase-amplitude coupling (PAC) in the subthalamic nucleus of Parkinson’s disease patients and finds that spiking activity synchronizes with high-frequency oscillations during PAC, correlating with beta burst duration.

This study shows that phase-dependent electrical stimulation can suppress beta oscillations in Parkinson's patients, offering a potential therapeutic strategy.