Aberrant RNA methylation triggers recruitment of an alkylation repair complex
Joshua R. Brickner, Ning Tsao, Rebecca Rodell, Clément Oyeniran, Valentina Lukinović, Albino Bacolla, Lisheng Zhang, Jennifer M. Soll, Alexandre G. Casanova, Adit Ganguly, Chuan He, John A. Tainer, Nicolas Reynoird, Nima Mosammaparast
The paper shows RNA alkylation triggers recruitment of the ASCC repair complex via RNF113A, revealing RNA damage as a signal for DNA repair.
bioRxiv · Aug 28, 2020 · PreprintMolecular Biology