Continuous mass photometry by single molecule trapping
Dan Loewenthal, Roi Asor, Stephen Austen Thorpe, Jack S. Peters, Konstantin Zouboulis, Merve Kaplan, Jan Christoph Thiele, Jack Bardzil, Seham Helmi, Sean Anthony Burnap, Tiong Kit Tan, Weston B. Struwe, Justin L. P. Benesch, Philipp Kukura
This paper introduces a method for continuous mass photometry of single molecules, enabling long-term observation of biomolecular interactions with high mass precision and temporal resolution.
Nature Methods · Oct 26, 2026Peer-reviewedBiophysics