Cell BiologybioRxivPreprint
Clonal hematopoiesis-associated DNMT3A mutations derepress bivalent Polycomb target genes and enhance macrophage migration
DOI 10.64898/2026.09.24.754138
Author
University of California, IrvineORCID 0000-0002-5212-2259Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Pranav Kannan, Daniel Helzer, Ekaterina I. Mokhonova…·Rachelle H. Crosbie
The paper shows that collagen abundance alone does not define fibrosis in DMD, as distinct matrix states with different biological activities and mechanosignaling exist.
Afrooz Rashnonejad, Manal Farea, Gholamhossein Amini Chermahini…·Scott Q. Harper
This study shows CRISPR-Cas13b effectively reduces DUX4 in FSHD but is limited by immune responses that decrease Cas13b levels over time.