Zhaoyu Li

The paper introduces LabGym, an open-source AI platform for automated analysis of C. elegans locomotion behavior in multi-worm videos with high accuracy.

The paper identifies a neuron-specific quality-control compartment, SolAS, that sequesters and expels misfolded proteins, showing its role in proteostasis during aging.

The paper shows that the C. elegans neuron RIM both promotes and suppresses locomotion behavior to fine tune motor output through dual neurotransmission mechanisms.

This study identifies the THO nuclear export complex as critical for synaptic transcript export, synapse development, and neuronal survival in dopaminergic neurons across species.