Author

Yanchun Chen

Chinese Academy of SciencesORCID 0000-0002-5267-0773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Baoxiang Zhuang· 1 shared Bian WuiD· 1 shared Chunjie Xu· 1 shared Chunli LiiD· 1 shared Fenghua Zhou· 1 shared Haiyan LiuiD· 1 shared Haoyun Zhang· 1 shared Hua XiangiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Baoxiang Zhuang

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2 papers

Recent·Most cited

METTL3-mediated m6A modification alleviates skeletal muscle atrophy in ALS by regulating ACSL1-dependent triglyceride metabolism

Qiupeng Yan, Lingyun Zhang, Xue Bai, Yingjun Guan, Haoyun Zhang, Jinmeng Liu, Baoxiang Zhuang, Mu Li, Xue Zhang, 陈晓苏, Xiaonan Ma, Chunjie Xu, Huilin Yang, Xin Huang, Fenghua Zhou, Yanchun Chen

This study identifies METTL3-mediated m6A modification as a regulator of triglyceride metabolism in ALS skeletal muscle, alleviating atrophy through ACSL1 expression.

bioRxiv · Oct 24, 2026 · PreprintNeuroscience

Computational redesign of a PETase for plastic biodegradation by the GRAPE strategy

Yinglu Cui, Yanchun Chen, Xinyue Liu, Saijun Dong, Yu’e Tian, Yuxin Qiao, Ruchira Mitra, Jing Han, Chunli Li, Xu Han, Weidong Liu, Quan Chen, Wenbin Du, Shuang‐Yan Tang, Hua Xiang, , Bian Wu

This paper computationally redesigns PETase to improve its stability and PET degradation efficiency using the GRAPE strategy.

bioRxiv · Oct 30, 2019 · PreprintSynthetic Biology