Author

Jing Han

Chinese Academy of SciencesORCID 0000-0002-9207-0238Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jing Han1 paper · Fudan University

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Hua XiangiD· 2 shared Bian WuiD· 1 shared Changjialian Yang· 1 shared Chunli LiiD· 1 shared Dahe ZhaoiD· 1 shared Haiyan LiuiD· 1 shared Haiying YuiD· 1 shared Jianfeng Chu· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Hua XiangORCID

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3 papers

Recent·Most cited

A Unified Structure-Based Deep-Learning Framework for High-Throughput Screening of Protein-Binding RNAs

Yihao Zhao, Jing Han, jike wang, Jianfeng Chu, Yu Kang, Tingjun Hou

PRIS improves protein-RNA interaction prediction and RNA library screening by combining structure selection and binding preference inference.

bioRxiv · Sep 8, 2026 · PreprintBioinformatics

Engineered minimal type I CRISPR-Cas system for transcriptional activation and base editing in human cells

Jing Guo, Luyao Gong, Haiying Yu, Ming Li, Qiaohui An, Zhenquan Liu, Shuru Fan, Changjialian Yang, Dahe Zhao, Jing Han, Hua Xiang

This paper develops a compact type I-F2 CRISPR-Cas system for transcriptional activation and base editing in human cells, achieving a wide editing window and high efficiency.

Nature Communications · Aug 23, 2024Peer-reviewedMolecular Biology

Computational redesign of a PETase for plastic biodegradation by the GRAPE strategy

Yinglu Cui, Yanchun Chen, Xinyue Liu, Saijun Dong, Yu’e Tian, Yuxin Qiao, Ruchira Mitra, Jing Han, Chunli Li, Xu Han, Weidong Liu, Quan Chen, Wenbin Du, Shuang‐Yan Tang, Hua Xiang, , Bian Wu

This paper computationally redesigns PETase to improve its stability and PET degradation efficiency using the GRAPE strategy.

bioRxiv · Oct 30, 2019 · PreprintSynthetic Biology