Author

Lisa A. Cosimi

Broad InstituteORCID 0000-0002-5269-1881Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Deborah Tan HungiD· 3 shared Abigail L. MansoniD· 1 shared Adam L. Essene· 1 shared Alejandro PirontiiD· 1 shared Alex K. ShalekiD· 1 shared Alexander SturmiD· 1 shared Alexandra–Chloé VillaniiD· 1 shared Alkes L. PriceiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersGenomics

Deborah Tan HungORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 22, 2025

Mapping genetic and phenotypic diversity of Pseudomonas aeruginosa across clinical and environmental isolation sites

Cristina Peñaranda, Evan Pierce Brenner, Anne E. Clatworthy…·Deborah Tan Hung

The paper analyzes 125 Pseudomonas aeruginosa isolates from clinical and environmental sources to assess genotype-phenotype correlations and niche specialization, finding that genomic diversity does not correlate with isolation source or most virulence traits, but Group B strains show higher cytotoxicity.

2 citations

bacteria (other)whole-genome sequencing

𝕏 PostBluesky

GenomicsGenome MedicinePeer-reviewedApr 4, 2022

Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

Rauf Salamzade, Abigail L. Manson, Bruce J. Walker…·Ashlee M. Earl

The paper develops a method to trace horizontal gene transfer and persistence of carbapenem resistance genes across bacterial species using genomic data from clinical isolates.

39 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintFeb 25, 2021

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

Toni Marie Delorey, Carly G.K. Ziegler, Graham Heimberg…·Alexandra–Chloé Villani

This study creates a single-cell and spatial atlas of autopsy tissues from COVID-19 patients, revealing altered cellular responses and potential therapeutic targets.

40 citations

humanscRNA-seq

𝕏 PostBluesky