Author

Adam L. Essene

Beth Israel Deaconess Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genomics· 2 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Linus T.-Y. TsaiiD· 3 shared Alex K. ShalekiD· 2 shared Alexander SturmiD· 2 shared Alexandra–Chloé VillaniiD· 2 shared Ayshwarya SubramanianiD· 2 shared Carly G.K. ZiegleriD· 2 shared Caroline B. M. PorteriD· 2 shared Christopher L. JacobsiD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Linus T.-Y. TsaiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rapid Remodeling of Human White Adipose Tissue Following Bariatric Surgery

Zinger Yang Loureiro, Gregory P. Westcott, Anton Gulko, Adam L. Essene, Zhibo Zhou, Wenle Liang, Christopher L. Jacobs, Soumya Nagesh, Nadejda Bozadjieva-Kramer, Randy J. Seeley, WILLIAM F. GOURASH, Joseph Loureiro, Lori L. Jennings, Robert Edgardo Gerszten, Anita P. Courcoulas, , Evan D. Rosen

This study identifies rapid remodeling of human subcutaneous white adipose tissue within one month after bariatric surgery using snRNA-seq, revealing changes in adipocyte populations and transcriptional dynamics.

bioRxiv · Apr 15, 2026 · PreprintPhysiology

A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

Yered H. Pita-Juárez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C. Melms, Sebastian Niezen, Toni Marie Delorey, Adam L. Essene, Olga Rachel Brook, Deepti B. Pant, Disha Skelton-Badlani, Pourya Naderi Yeganeh, Pinzhu Huang, Liuliu Pan, TYLER D. HETHER, Tallulah S. Andrews, , Ioannis S. Vlachos

This study creates a single-nucleus and spatial transcriptomic atlas of the COVID-19 liver, revealing cellular and functional disruptions associated with organ damage.

Genome biology · Mar 14, 2025Peer-reviewedGenomics

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

Toni Marie Delorey, Carly G.K. Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Åsa Segerstolpe, Domenic Abbondanza, Stephen J. Fleming, Ayshwarya Subramanian, Daniel T. Montoro, Karthik A. Jagadeesh, Kushal K. Dey, Pritha Sen, Michal Slyper, Yered H. Pita-Juárez, , Alexandra–Chloé Villani

This study creates a single-cell and spatial atlas of autopsy tissues from COVID-19 patients, revealing altered cellular responses and potential therapeutic targets.

bioRxiv · Feb 25, 2021 · PreprintGenomics