Efficacy of Deferoxamine Mesylate in Serum and Serum-Free Media: Adult Schwann Cell Survival Following Hydrogen Peroxide Induced Cell Death
Yee H.E. Ma, Abhinay Reddy Putta, Cyrus H. H. Chan, Stephen Ryan Vidman, Paula V. Monje, Giles W. Plant
This study shows that Deferoxamine Mesylate (DFO) enhances Schwann cell survival in serum-containing media but not in serum-free conditions, with increased autophagy and Hif1a expression observed in serum-free environments.
bioRxiv · Jan 23, 2025 · PreprintNeuroscience