Author

Alexander Brack

Universitätsklinikum WürzburgORCID 0000-0002-3541-7063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:imaging· 3 Research Focus:differential expression· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Heike Lydia RittneriD· 4 shared Annemarie SodmanniD· 2 shared Beate HartmannsbergeriD· 2 shared Claudia SommeriD· 2 shared Felicitas SchlottiD· 2 shared Kathrin DoppleriD· 2 shared Robert BlumiD· 2 shared Thorsten BischleriD· 2 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersNeuroscience

Heike Lydia RittnerORCID

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4 papers

Recent·Most cited

Sex differences define the molecular and cellular phenotypes of pain resolution in dorsal root ganglia

Felicitas Schlott, Beate Hartmannsberger, Thorsten Bischler, Tom Gräfenhan, Alexander Brack, Heike Lydia Rittner, Annemarie Sodmann, Robert Blum

This study identifies sex-specific molecular and cellular differences in rat dorsal root ganglia during pain resolution after nerve injury.

Cell Reports · May 28, 2026Peer-reviewedNeuroscience

TAM receptors mediate the Fpr2-driven pain resolution and fibrinolysis after nerve injury

Beate Hartmannsberger, Adel Ben-Kraiem, Sofia Kramer, Carolina Guidolin, Ida Kazerani, Kathrin Doppler, Dominique Thomas, Robert Gurke, Marco Sisignano, Pranav P. Kalelkar, Andrés J. Garcı́a, Paula V. Monje, Michael Sammeth, Asma Nusrat, Alexander Brack, , Heike Lydia Rittner

This study identifies the Fpr2-Cd206-TAM receptor axis as a target for pain resolution and fibrinolysis after nerve injury by resealing capillary barriers.

Acta Neuropathologica · Dec 16, 2024Peer-reviewedNeuroscience

Human dorsal root ganglia after plexus injury: either preservation or loss of the multicellular unit

Annemarie Sodmann, Johannes Degenbeck, Annemarie Aue, Magnus Schindehütte, Felicitas Schlott, Panagiota Arampatzi, Thorsten Bischler, Max Schneider, Alexander Brack, Camelia Maria Monoranu, Tom Gräfenhan, Michael Bohnert, Mirko Pham, Gregor Antoniadis, Robert Blum, Heike Lydia Rittner

The paper examines human dorsal root ganglia (DRG) after plexus injury, finding two types of outcomes: neuronal preservation or loss, with implications for treatment strategies.

British Journal of Anaesthesia · Oct 10, 2024Peer-reviewedNeuroscience

Claudin-12 deficiency causes nerve barrier breakdown, mechanical hypersensitivity and painful neuropathy

Jeremy Tsung-Chieh Chen, Xiawei Hu, Kathrin Doppler, Olga Breitkreuz-Korff, Isabel U. C. Otto, Joachim Schwabe, Ann‐Kristin Reinhold, Dorothee Günzel, Sophie Dithmer, Mohammed K. Hankir, Petra Fallier‐Becker, Lars Winkler, Rosel Blasig, Claudia Sommer, Alexander Brack, , Heike Lydia Rittner

This study identifies claudin-12's role in maintaining myelin and blood-nerve barriers, showing its deficiency causes mechanical hypersensitivity and painful neuropathy in male mice.

bioRxiv · Nov 26, 2019 · PreprintNeuroscience