Simon P. Poland

This paper introduces TomoFLIM, a high-speed multiphoton FLIM technique that enables rapid, accurate imaging of dynamic biological processes with compression ratios over 90%.

This study identifies NHSL3 as a regulator of actin dynamics by interacting with Ena/VASP proteins and the Scar/WAVE complex, inhibiting Arp2/3 activity to promote cell migration.

This paper develops a three-color Cascade-FRET system to measure force-dependent interactions between RIAM and vinculin in focal adhesions, revealing force-independent binding and tension-sensing capabilities.