Luca Masin

The paper identifies an interferon-responsive oligodendroglial state in aging white matter using killifish models, linking it to potential neurodegenerative disease mechanisms.

The paper shows that dendritic pruning, linked to suppressed mTORC1 signaling, supports axonal regeneration in zebrafish, revealing a trade-off between dendritic preservation and axonal growth.

The paper compares retinal ganglion cell resilience to optic nerve injury across mice, zebrafish, and killifish, revealing species-specific differences in RGC density and injury response.

This study shows that retinal ganglion cell regenerative potential is linked to their developmental maturation timeline, with sON cells showing greater injury-induced regression than tON cells.

The paper identifies metabolic reprogramming in zebrafish axonal regeneration and shows its conservation in mammals, suggesting therapeutic potential for CNS regeneration.

The paper shows that local glycolysis supports axonal regeneration after injury by providing ATP, complementing mitochondrial metabolism.

This study shows that loss of Pcdh10 in interneurons affects socio-affective communication in mice, with heterozygous pups showing more pronounced behavioral changes.

This study uses bulk and single-cell RNA-seq to analyze age-related transcriptome changes in the African turquoise killifish retina, identifying oxidative stress, gliosis, and inflammageing, and highlighting dysregulation of retinal disease genes.

The paper optimizes a whole-mount multiplexed RNA in situ hybridization chain reaction (HCR v3.0) protocol combined with immunohistochemistry and imaging to visualize neurogenesis in octopus embryos.

This study shows that the AppNL-G-F mouse retina accumulates Aβ early and exhibits AD-like features, suggesting it as a model for preclinical AD research and diagnosis.