Lies De Groef

Human Myelin Spheres for In Vitro Oligodendrocyte Maturation, Myelination and Neurological Disease Modeling

This paper introduces human myelin spheres (MyS) as a model for studying myelination and demyelination, showing their ability to form myelinated neurons and mimic in vivo oligodendrocyte development.

Local glycolysis supports injury-induced axonal regeneration

The paper shows that local glycolysis supports axonal regeneration after injury by providing ATP, complementing mitochondrial metabolism.

A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome

This study investigates the role of oligodendroglia in Wolfram syndrome using mouse models and iPSC-derived cells, finding preserved oligodendroglia function and suggesting alternative targets for treatment.

Corticotropin-Releasing Factor Induces Functional And Structural Synaptic Remodelling In Acute Stress

This study shows CRF rapidly alters synaptic function and structure in hippocampal CA1 neurons during acute stress, enhancing synaptic communication and memory consolidation.

The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research

This study shows that the AppNL-G-F mouse retina accumulates Aβ early and exhibits AD-like features, suggesting it as a model for preclinical AD research and diagnosis.