Author

Marta Martín‐Izquierdo

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-5290-2116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Elena VueltaiD· 1 shared Fermin M. Sanchez-GuijoiD· 1 shared Ignacio García‐TuñóniD· 1 shared Jesús María Hernández-SáncheziD· 1 shared Jesús María Hernández‐RivasiD· 1 shared Julián SevillaiD· 1 shared Lucía Méndez· 1 shared Manuel Sánchez‐MartíniD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Elena VueltaORCID

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1 paper

Recent·Most cited

Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency

Ignacio García‐Tuñón, Verónica Alonso-Pérez, Elena Vuelta, Sandra Pérez‐Ramos, María Herrero, Lucía Méndez, Jesús María Hernández-Sánchez, Marta Martín‐Izquierdo, Raquel Saldaña, Julián Sevilla, Fermin M. Sanchez-Guijo, Jesús María Hernández‐Rivas, Manuel Sánchez‐Martín

This study shows that targeting splice donor sites with sgRNAs improves CRISPR/Cas9 knockout efficiency by increasing frameshift mutations and disrupting pre-mRNA splicing.

PLoS ONE · May 9, 2019Peer-reviewedMolecular Biology