Gil Bub

RhythmWriter quantifies contractile motion in hiPSC-CMs, enabling high-throughput drug screening and maturation assessment.

This paper uses reinforcement learning to discover new mechanisms of reentry in excitable media, including subthreshold stimulation strategies that induce unidirectional propagation and reentry.

iMyocyte is a web-based platform that uses a cellular automaton model to demonstrate cardiac reentry dynamics in real time, allowing students to manipulate parameters and observe effects on wave propagation.

The paper uses optogenetic stimulation and computational models to analyze phase resetting in human iPSC-derived cardiomyocytes, showing how it explains cardiac arrhythmias and offers strategies to prevent them.

This paper develops a real-time digital heart twin system that integrates optogenetic cardiac monolayers with GPU-accelerated simulations to study reentrant arrhythmias.

The paper demonstrates the Exeter Multiscope's ability to rapidly acquire and analyze image data from cardiomyocyte monolayers to measure contraction.